Neurological Problems caused by Gut Disease
- Lea Kasten
- Dec 8, 2023
- 1 min read
Neurological problems can be caused by stressors such as headaches and migraines, but can gut diseases also be the cause? As this study has been started, a growing body of data suggests a role for the microbiota in modulating behaviors relevant to stress-related disorders, with preclinical models utilizing experimental conditions like probiotics, antibiotics, fecal microbial transplant, and comparisons between germ-free and pathogen-free microbiome environments. Many of the previous links that have been made between the microbiome-brain links were overlooked because other reasons for the neurological problems have been more plausible.
As seen on this representation, the channels between the gut and brain can send microbiota such as endocrine, neurocrine and inflammation signals that will affect the microbial composition and function of the brain. For example, maternal separation, restraint conditions, crowding, heat stress, and acoustic stress all alter the composition of the gut microbiota and can therefore be some of the factors that create neurological problems coming from the gut.
Even though most of the studies have been tested on rodents with the data then also being based on rodent species, it is a heavily believed notion that the same applies for human brain structure and the microbiota in our guts. Some of the most recent studies such as Cristofori F. Dargenio’s study and Yuan R. Yang collected data from humans in 2021 and ended up proving this notion to be true
Sources by Claire Maier:
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